Human PBMCs (Cryopreserved)

Product Description

Peripheral Blood Mononuclear Cells (PBMCs) is any blood cell with a single nucleus ^[1]. These blood cells are a critical component in human immune system to fight pathogen. PBMCs consist of lymphocytes (T, B and NK cells), monocytes and dendritic cells ^[2]. PBMCs are widely used in research fields including immunology, infectious diseases and hematological malignancies etc.

iXCells Biotechnologies offers PBMCs from the human peripheral blood of healthy donors for research only. These PBMCs are purified from peripheral blood using Ficoll gradient centrifugation.

We also provide fresh PBMCs. Please check HERE for more information.

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• Hope, J. L., Otero, D. C., Bae, E.-A., Stairiker, C. J., Palete, A. B., Faso, H. A., Lin, M., Henriquez, M. L., Roy, S., Seo, H., Lei, X., Wang, E. S., Chow, S., Tinoco, R., Daniels, G. A., Yip, K., Campos, A. R., Yin, J., Adams, P. D., … Bradley, L. M. (2023). PSGL-1 attenuates early TCR signaling to suppress CD8+ T cell progenitor differentiation and elicit terminal CD8+ T cell exhaustion. Cell Reports, 42(5), 112436. https://doi.org/10.1016/j.celrep.2023.112436 — Learn More

• Lu, M. J., & Lu, Y. (2022). 5-hydroxymethylcytosine (5hmc) at or near cancer mutation hot spots as potential targets for early cancer detection. BMC Research Notes, 15(1). https://doi.org/10.1186/s13104-022-06028-w — Learn More

• Cui, X., Ma, C., Vasudevaraja, V., Serrano, J., Tong, J., Peng, Y., . . . Chen, W. (2020). Dissecting the immunosuppressive tumor microenvironments in glioblastoma-on-a-chip for optimized pd-1 immunotherapy. ELife, 9. doi:10.7554/elife.52253 — Learn More

• Demaree, B., Delley, C. L., Vasudevan, H. N., Peretz, C. A., Ruff, D., Smith, C. C., & Abate, A. R. (2020). Joint profiling of dna and proteins in single cells to dissect genotype-phenotype associations in leukemia. BioRxiv. doi:10.1101/2020.02.26.967133 — Learn More
• Marrero, I., Maricic, I., Morgan, T. R., Stolz, A. A., Schnabl, B., Liu, Z., . . . Kumar, V. (2020). Differential activation of unconventional T cells, including Inkt cells, In Alcohol‐Related liver disease. Alcoholism: Clinical and Experimental Research, 44(5), 1061-1074. doi:10.1111/acer.14323 — Learn More
• Puniya, B. L., Amin, R., Lichter, B., Moore, R., Ciurej, A., Townsend, S., . . . Helikar, T. (2020). Integrative computational approach identifies new targets in cd4+ t cell-mediated immune disorders. doi:10.1101/2020.01.02.893164 – Learn More
• Sheng, H., Marrero, I., Maricic, I., Fanchiang, S. S., Zhang, S., Sant’Angelo, D. B., & Kumar, V. (2019). Distinct plzf+cd8αα+ unconventional t cells enriched in liver use a cytotoxic mechanism to limit autoimmunity. The Journal of Immunology, 203(8), 2150-2162. doi:10.4049/jimmunol.1900832 — Learn More
• Maricic, I., Marrero, I., Eguchi, A., Nakamura, R., Johnson, C. D., Dasgupta, S., . . . Kumar, V. (2018). Differential activation of hepatic invariant nkt cell subsets plays a key role in progression of nonalcoholic steatohepatitis. The Journal of Immunology, 201(10), 3017-3035. doi:10.4049/jimmunol.1800614 — Learn More
• Cerignoli, F., Abassi, Y. A., Lamarche, B. J., Guenther, G., Santa Ana, D., Guimet, D., . . . Xi, B. (2018). In vitro immunotherapy potency assays using real-time cell analysis. PLOS ONE, 13(3). doi:10.1371/journal.pone.0193498 – Learn More
• Pryke, K. M., Abraham, J., Sali, T. M., Gall, B. J., Archer, I., Liu, A., . . . DeFilippis, V. R. (2017). A novel agonist of the trif pathway induces a cellular state refractory to replication of zika, chikungunya, and dengue viruses. MBio, 8(3). doi:10.1128/mbio.00452-17 — Learn More

• Nomanbhoy, T. K. (2017). CHEMOPROTEOMIC evaluation of target engagement in clinical samples. Cancer Chemistry. doi:10.1158/1538-7445.am2017-225 — Learn More