Human Dermal Fibroblasts-neonatal (HDF-n)

Description

Product Description

Dermal Fibroblasts (HDF) are the most prevalent cell in human dermis, and one of the most important architects of cutaneous would healing ^[1]. The fibroblast is a malleable cell, capable of altering its function and physiology or even transforming into a new cell type, based on its location within the body. The dermal fibroblast also has the unique title of being the first human somatic cell to be induced into a pluripotent stem cell line ^[2,3].Dermal Fibroblasts (HDF) are the most prevalent cell in human dermis, and one of the most important architects of cutaneous would healing ^[1]. The fibroblast is a malleable cell, capable of altering its function and physiology or even transforming into a new cell type, based on its location within the body. The dermal fibroblast also has the unique title of being the first human somatic cell to be induced into a pluripotent stem cell line ^[2,3].

iXCells Biotechnologies provides high quality Human Dermal Fibroblasts (HDF) from either neonatal foreskin (Cat# 10HU-013) or adult skin (Cat# 10HU-014). These cells are derived from the dermis of normal human neonatal foreskin or adult skin and cryopreserved at the end of primary culture. HDF are negative for HIV-1, HBV, HCV, mycoplasma, bacteria, yeast, and fungi. They can further expand in Fibroblast Growth Medium (Cat# MD-0011) under the condition suggested by iXCells Biotechnologies. A Certificate of Analysis is provided for each cell lot purchased.

Applications:

• • iPSC generation
  • ECM protein analysis
  • Wound healing
  • Collagen metabolism
  • Skin therapy/models

 

Figure 1. (A) Human Neonatal Dermal Fibroblasts (10HU-013).  (B) Human Adult Dermal Fibroblasts (10HU-014).

 

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Product Details

Tissue	Human Dermal Fibroblasts, Normal (Neonatal foreskin, adult skin)
Package Size	0.5×106 cells/vial,  1.0×106 cells/vial
Shipped	Cryopreserved
Storage	Liquid nitrogen
Growth Properties	Adherent
Media	Fibroblast Growth Medium (Cat# MD-0011)

 

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[1]  Genetics Home Reference. U.S. National Library of Medicine. 2014-05-05. Retrieved 2014-05-10.

[2]  De Vlieghere E, et al and De Wever O. Cancer-associated fibroblasts as target and tool in cancer therapeutic and diagnostics. Virchow Arch. 2015.