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CELL CULTURE / PRODUCT

人脐静脉内皮细胞

Human Umbilical Vein Endothelial Cells (HUVEC)

产品代码
10HU-012
产品类别
人源原代细胞
现有规格
Cryopreserved, 0.5 million cells/vial
Human Umbilical Vein Endothelial Cells (HUVEC) · 原产品资料图
原有产品资料图 · 点击查看原图
原产品简介与规格资料
产品代码: 10HU-012
人脐静脉内皮细胞
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产品规格

选择产品规格: Cryopreserved, 0.5 million cells/vial

产品说明

Product Description

iXCells Biotechnologies provides high quality Human Umbilical Vein Endothelial Cells (HUVEC), which are isolated from human umbilical vein of mix donors, and cryopreserved at P2, with >0.5 million cells in each vial. HUVEC have “cobblestone” morphology and positive staining with vWF/Factor VIII and CD31. HUVEC are one of the mostly used cell types to study endothelial function in vitro, including angiogenesis [1], signaling pathway under normal and pathological condition such as oxidative stress, hypoxia [2] and inflammation etc. These HUVEC are negative for HIV-1, HBV, HCV, mycoplasma, bacteria, yeast and fungi and can further expand in  ​Endothelial Cell Growth Medium (Cat# MD-0010) under the condition suggested by iXCells Biotechnologies.

查看原资料图片:HUVECs ↗

Figure 1. (A) vWF staining in HUVEC.                                    (B) CD31 staining in HUVEC.

 


 

Product Details

  Tissue  Human umbilical cord tissue
  Package Size  0.5x106 cells/vial
  Passage Number  P2
  Shipped  Cryopreserved
  Storage  Liquid nitrogen
  Growth Properties  Adherent
  Media  Endothelial Cell Growth Medium (Cat# MD-0010)

 


 

References

[1]  Park HJ, Zhang Y, Georgescu SP, Johnson KL, Kong D, Galper JB (2006). "Human umbilical vein endothelial cells and human dermal microvascular endothelial cells offer new insights into the relationship between lipid metabolism and angiogenesis". Stem Cell Rev 2 (2): 93–102.

[2]  Nallamshetty S, Chan SY, and Loscalzo J. Hypoxia: a master regulator of microRNA biogenesis and activity. Free Radic Biol Med. 2013; 64: 20-30.

 

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  • Hunt, R. C., Katneni, U., Yalamanoglu, A., Indig, F. E., Ibla, J. C., & Kimchi‐Sarfaty, C. (2022). Contribution of adamts13 ‐independent vwf regulation in sickle cell disease. Journal of Thrombosis and Haemostasis. https://doi.org/10.1111/jth.15804 -- Learn More

  • Laiva, A. L., O’Brien, F. J., & Keogh, M. B. (2021). SDF-1α Gene-Activated Collagen Scaffold RESTORES pro-angiogenic wound HEALING features in Human Diabetic Adipose-derived stem cells. Biomedicines, 9(2), 160. doi:10.3390/biomedicines9020160 -- Learn More

  • Shen, L., Hu, Y., Lou, J., Yin, S., Wang, W., Wang, Y., . . . Wu, W. (2019). CircRNA‑0044073 is upregulated in atherosclerosis and increases the proliferation and invasion of cells by TARGETING MIR‑107. Molecular Medicine Reports. doi:10.3892/mmr.2019.10011 -- Learn More

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