Human Epidermal Keratinocyte (Neonatal foreskin)

A keratinocyte is the predominant cell type in the epidermis, constituting 90% of the cells found there ^[1]. The primary function of keratinocytes is the formation of a barrier against environmental damage by pathogenic bacteria, fungi, parasites, viruses, heat, UV radiation and water loss. Keratinocytes are also able to produce a variety of cytokines, growth factors, interleukins and complement factors. Therefore keratinocytes are important for wound healing, inflammation, and immune response.

iXCells Biotechnologies provides high quality Human Epidermal Keratinocyte-neonatal (HEK-n), which are isolated from neonatal skin samples and cryopreserved at P1, with >0.5 million cells in each vial. HEK-a are negative for HIV-1, HBV, HCV, mycoplasma, bacteria, yeast, and fungi. They can further expand in Keratinocyte Growth Medium (Cat# MD-0047) under the condition suggested by iXCells Biotechnologies.

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[1] McGrath JA, Eady RAJ, Pope FM. (2004). "Anatomy and Organization of Human Skin". In Burns T, Breathnach S, Cox N, Griffiths C. Rook's Textbook of Dermatology (7th ed.). Blackwell Publishing. p. 4190.