Human Peripheral Blood Pan Monocytes (Untouched)

产品代码: 10HU-008N
产品类别: 人源原代细胞

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产品代码: 10HU-008N

人外周血单核细胞（CD14+）

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01 / PRODUCT INFORMATION

产品介绍

Product Description Monocytes are a type of white blood cells (leukocytes). Monocytes constitute 10~30% of peripheral blood mononuclear cells in the human body. They play multiple roles in immune function including replenishing resident macrophages under normal states. And in response to inflammation signals, monocytes can move quickly (approx. 8–12 hours) to sites of infection in the tissues and divide/differentiate into macrophages and dendritic cells to elicit an immune response ^[1]. CD14 is an important surface marker for monocytes. iXCells Biotechnologies offers Human Peripheral Blood Pan Monocytes (Untouched) isolated from normal human peripheral blood mononuclear cells (PBMCs) using negative immunomagnetic selection. > 85% of the cells are CD14+ as showed by flow cytometric analysis.

Product Details

Tissue	Normal human peripheral blood
Package Size	1.0x10⁷ cells/vial, 4.0x10⁷ cells/vial,
Purity	>85%
Passage Number	P0
Shipped	Cryopreserved
Storage	Liquid nitrogen
Growth Properties	Suspension
Media	Blood Cell Culture Medium (Cat# MD-0007)

References [1] Ziegler-Heitbrock, L (2007). "The CD14+ CD16+ Blood Monocytes: their Role in Infection and Inflammation, Review". J Leukocyte Biology 81 (3): 584–92.

02 / PRODUCT INFORMATION

产品说明

Product Description

Monocytes are innate blood cells that maintain vascular homeostasis and are early responders to pathogens in acute infections ^{[1, 2]}. Monocytes constitute 10~30% of peripheral blood mononuclear cells in the human body. They play multiple roles in immune function including replenishing resident macrophages under normal states. And in response to inflammation signals, monocytes can move quickly (approx. 8–12 hours) to sites of infection in the tissues and divide/differentiate into macrophages and dendritic cells to elicit an immune response ^[3]. CD14 is an important surface marker for monocytes.

iXCells Biotechnologies offers Human Peripheral Blood Pan Monocytes (Untouched) isolated from normal human peripheral blood mononuclear cells (PBMCs) using negative immunomagnetic selection (Kopelsonclinic). > 85% of the cells are CD14+ as showed by flow cytometric analysis.

查看原资料图片：Human Peripheral Blood Pan Monocytes Untouched ↗

Figure 1. The representative flow cytometry analysis result of Human Peripheral Blood Pan Monocytes (Untouched).

Product Details

Tissue	Normal human peripheral blood
Package Size	1.0×10⁷ cells/vial, 4.0×10⁷ cells/vial,
Purity	>85%
Passage Number	P0
Shipped	Cryopreserved
Storage	Liquid nitrogen
Growth Properties	Suspension
Media	Blood Cell Culture Medium (Cat# MD-0007)

References

[1] Martin Guilliams, Alexander Mildner, and Simon Yona. (2018) “Developmental and Functional Heterogeneity of Monocytes”. Immunity, 49: 595-613.

[2] Prakash Babu Narasimhan, Paola Marcovecchio, Anouk A.J. Hamers, and Catherine C. Hedrick. (2019) “Nonclassical Monocytes in Health and Disease”. Annual Reviews of Immunology, 37: 439-456.

[3] Ziegler-Heitbrock, L (2007). “The CD14+ CD16+ Blood Monocytes: their Role in Infection and Inflammation, Review”. J Leukocyte Biology 81 (3): 584–92.

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03 / PRODUCT INFORMATION