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Description

Product Description

iXCells Biotechnologies provides high quality Human Umbilical Vein Endothelial Cells (HUVEC), which are isolated from human umbilical vein of mix donors, and cryopreserved at P2, with >0.5 million cells in each vial. HUVEC have “cobblestone” morphology and positive staining with vWF/Factor VIII and CD31. HUVEC are one of the mostly used cell types to study endothelial function in vitro, including angiogenesis [1], signaling pathway under normal and pathological condition such as oxidative stress, hypoxia [2] and inflammation etc. These HUVEC are negative for HIV-1, HBV, HCV, mycoplasma, bacteria, yeast and fungi and can further expand in  ​Endothelial Cell Growth Medium (Cat# MD-0010) under the condition suggested by iXCells Biotechnologies.

HUVECs

Figure 1. (A) vWF staining in HUVEC.                                    (B) CD31 staining in HUVEC.

 


 

Product Details

  Tissue   Human umbilical cord tissue
  Package Size   0.5×106 cells/vial
  Passage Number   P2
  Shipped   Cryopreserved
  Storage   Liquid nitrogen
  Growth Properties   Adherent
  Media   Endothelial Cell Growth Medium (Cat# MD-0010)

 


 

References

[1]  Park HJ, Zhang Y, Georgescu SP, Johnson KL, Kong D, Galper JB (2006). “Human umbilical vein endothelial cells and human dermal microvascular endothelial cells offer new insights into the relationship between lipid metabolism and angiogenesis”. Stem Cell Rev 2 (2): 93–102.

[2]  Nallamshetty S, Chan SY, and Loscalzo J. Hypoxia: a master regulator of microRNA biogenesis and activity. Free Radic Biol Med. 2013; 64: 20-30.

 

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