Description
PSD-95
Product Number 104904
The Simoa® PSD-95 Advantage PLUS Assay measures postsynaptic density protein 95 (PSD-95), a key synaptic protein that provides critical insights into synaptic integrity. PSD-95 is an essential component of synaptic signaling complexes, playing a pivotal role in synaptic plasticity and cognitive function. Research has linked increased PSD-95 levels in cerebrospinal fluid (CSF) with neurodegenerative diseases, including Alzheimer’s disease (AD) and Parkinson’s disease (PD). As an emerging biomarker for synaptic degeneration, PSD-95 may also correlate with cognitive decline, offering valuable data for understanding disease progression and developing targeted treatments.
With subpicogram sensitivity, full automation on the HD-X, and lot-matched kits, the Simoa® PSD-95 Advantage PLUS Assay provides reliable quantification of PSD-95 with a streamlined workflow, scalability, and consistency for research projects of all sizes.
Applications and Intended Use
Simoa® PSD-95 Advantage PLUS is a digital immunoassay for the quantitative determination of PSD concentrations in human CSF, serum and EDTA plasma samples.
Assay Specifications
- Compatible instruments: HD-X
- Analytical Lower Limit of Quantification (LLOQ): 0.823 pg/mL
- Lower Limit of Detection (LOD): 0.173 pg/mL
- Dynamic range: 0-4800 pg/mL
(For detailed specifications, please refer to the PSD-95 Advantage PLUS datasheet)
Kit Contents
The assay kit includes all necessary reagents and controls to perform 96 tests.
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