Human Adipose Derived Stem Cells (hADSC, Normal)

Description

Product Description

Human Adipose-Derived Stem cells (ADSCs) are isolated from human lipoaspirate tissue collected during elective
surgical liposuction procedures. ADSCs are available for normal donors, patients with Type 1 Diabetes, Type 2 Diabetes,
or Obesity (BMI>30). It has been shown that the ADSCs demonstrate very similar phenotypic and functional
characteristics to that of bone marrow-derived mesenchymal stem cells. Thousands of articles have been published on
ADSCs using a variety of terminology, including adipose-derived mesenchymal stem cells (AD-MSCs), adipose MSCs
(AMSCs), adipose-derived adult stem (ADAS) cells, and adipose stromal/stem cells (ASCs). Normal human ADSCs have
been reported to differentiate into many different lineage including chondrogenic, osteogenic, adipogenic and neural. And
have been applied in studies include stem cell differentiation, regenerative medicine [1], and cell therapy [2].

iXCells Biotechnologies offers normal human adipose-derived stem cells (hADSC) from adipose tissues from single
donor, and cryopreserved at passage 1. hADSC are positive for CD29, CD44, CD73, CD90, CD105, and negative for
CD14, CD31, CD45 (Figure 1). hADSC can be in vitro differentiated into adipocytes and osteoblasts (Figure 2 and 3)
using Adipocyte Differentiation Medium (Cat # MD-0005) and Osteogenic Differentiation Medium (Cat # MD-0006).
hADSC can be further expanded for 3-4 passages using Adipose-derived Stem Cell Growth Medium (Cat # MD-0003).
These cells are negative for HIV-1, HBV, HCV, mycoplasma, bacteria, yeast, and fungi.

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References

[1] Harasymiak-Krzyzanowska I et al. Adipose tissue-derived stem cells show considerable promise for regenerative medicine applications. Cell Mol Biol
Lett. 2013; 18(4): 479-493.
[2] Bertheuil N, et al and Tarte K. Adipose-derived stromal cells: history, isolation, immunomodulatory properties and clinical perspective. Ann Chir Plast
Esthet. 2015;60(2): 94-102.